Preheat the oven to 350°F (175°C). Grease and flour a 12-cup bundt cake pan.
In a medium bowl, whisk together the flour, baking powder, baking soda, and salt.
In a large bowl, using an electric mixer, cream the butter and sugar until light and fluffy.
Add the eggs one at a time, beating well after each addition.
Beat in the lemon zest and vanilla extract.
Add the flour mixture in three additions, alternating with the milk, beginning and ending with the flour mixture. Mix until just combined.
Fold in the blueberries.
Pour the batter into the prepared pan and smooth the top with a spatula.
Bake for 50-60 minutes, or until a toothpick inserted into the center of the cake comes out clean.
Let the cake cool in the pan for 10 minutes before transferring it to a wire rack to cool completely.